Tandy has changed his centres and also rotates his fly-half, with Dan Edwards coming back in after Sam Costelow got a crack in Argentina.
Ospreys’ Edwards has started 10 of 12 internationals played this season, with Scarlets’ Costelow impressing until injured against Scotland and then facing the Pumas.
Last week’s starter drops out of the matchday 23 and centre Hawkins will be the cover at Kings Park.
“I feel a bit sensitive towards the way that 10s are treated because I played a lot of my career there,” said Anscombe.
“The one thing that they need to be careful about is chopping and changing. With 10s, regardless of how they play, there are times when you need to give them three or four games in a row.
“A 10’s job isn’t just about effort and attitude, so much is about decision-making and being accurate within that.
“When you keep chopping and changing it’s really tough to get a feel for that. You need time in the saddle to be making those decisions at the line constantly.”
Wales finish their season with Edwards, Thomas and Llewellyn at 10-12-13 and Tandy has a break until the selection headaches return in November.
