Houston’s pass rush has wreaked havoc this season, helping the Texans to a 12-5 record and a third straight play-off appearance.
And they gave Rodgers a torrid time on his 23rd play-off appearance and first in four years.
The one-time Super Bowl winner failed to get the Steelers offence going, although their defence also made life difficult for Houston quarterback CJ Stroud.
They forced the game’s first three turnovers – two from Stroud fumbles, plus an interception – but the best Pittsburgh could muster on the following possessions was a solitary field goal.
That made the half-time score 7-6, with Christian Kirk having scored a touchdown for Houston, before their defensive pressure paid off in the final quarter.
Rodgers fumbled after being sacked by Will Anderson and Sheldon Rankins recovered the loose ball to score a 33-yard touchdown.
Woody Marks then got into the end zone with a 13-yard rush and four plays later Rodgers was intercepted by Calen Bullock, who returned it for a 50-yard touchdown.
Rodgers holds the best passer rating (102.2) and interception rate (1.4%) of all-time so to finish with a pick-six and a passer rating of 50.8 would be far from a fitting farewell.
The Steelers are believed to be open to welcoming Rodgers back for what would be a 22nd NFL season, but speaking after Monday’s game, he said he would now “get away and have the right kind of conversations”.
“I’m not going to be making any emotional decisions,” Rodgers added. “It’s been a fun year so it’s disappointing to be sitting here with the season over.”
While Houston have boosted their hopes of reaching their first Super Bowl, Rodgers must contemplate ending his career with just one appearance in the NFL’s championship game.
That came in 2011, when Rodgers led the Green Bay Packers to victory over Pittsburgh, but he and the Steelers have yet to get back to the big game.
Pittsburgh’s head coach Mike Tomlin could also be set for a change as the Steelers have now lost their past seven play-off games and it is nine years since their last post-season victory.

